代表性论文
1.Y. Wang, J. N. Chen, X. Hua, X. B. Meng, H. Cai, R. Wang, J. Shi, H. T. Deng, L. Liu, Y.-M. Li*. Photocaging of Activity-Based Ubiquitin Probes via a C-Terminal Backbone Modification Strategy.Angew. Chem. Int. Ed. 2022, 61, e202203792.
2.Y. Wang, Q. Xia, X. Hua, Y. Y. Guo, J. Shi *, Y.-M. Li*. Semi-synthesis of biotin-bearing activity-based ubiquitin probes through sequential enzymatic ligation, N-S acyl transfer and aminolysis reaction. Chin. Chem. Lett. 2023, 34, 108010.
3.Y. Wang, C. C. Chen, X. B. Meng, J. Fan, M. Pan, J. N. Chen, Y. H. Wang, L. Xu, C. L. Tian, H. T. Deng, J. Shi *, Y.-M. Li*. Chemical Synthesis of diSUMO Photoaffinity Probes for the Identification of PolySUMO Chain-Specific Interacting Proteins. CCS. Chem. 2020, 2, 1157-1168.
4.Y. Wang, R. Wang, P Li, R. Yuan, Y.-M. Li , J. Shi *. Fmoc-SPPS-compatible p-methoxyphenacyl-modified Glutamic for the synthesis of photocaged peptides. Tetrahedron Lett. 2023, 116, 154339.
5.Chen, J, Wang, Y*, Wang, R, Yuan, R, Chu, G. C*, Li, Y. M*. Chemical synthesis of on demand-activated SUMO-based probe by a photocaged glycine-assisted strategy. Bioorg. Med. Chem. Lett. 2023, 94, 129460.
6.L. J. Liang#, Y. Wang#, X. Hua#, R. Yuan, Q. Xia, R. Wang, C. Li, G. Chu, L. Liu*, Y.-M. Li*. A cell-permeable stimuli-responsive ubiquitin probe for time-resolved monitoring of substrate ubiquitination in live cells. JACS Au 2023, 3, 2873-2882. (#: equal contribution)
7.Y. Xu#, Y. Wang#, P. Liu, G. C. Chu, H. Xu, Y.-M. Li, J. Wang*, J. Shi*. Catalyst free hydrazone ligation for protein labeling and modification using electron-deficient benzaldehyde reagents. Org. Biomol. Chem. 2018, 16, 7036-7040. (#: equal contribution)
8.X. Sui, Y. Wang, Y. X. Du, L. J. Liang, Q. Zheng, Y.-M. Li*, L. Liu *. Development and application of ubiquitin-based chemical probes. Chem. Sci. 2020, 11, 12633-12646.
9.L. Xu, J. Fan, Y. Wang, Z. P. Zhang, Y. Fu, Y. M. Li *, J. Shi *. An activity-based probe developed by a sequential dehydroalanine formation strategy targets HECT E3 ubiquitin ligases. Chem. Commun. 2019, 55, 7109-7112.
10.X. Hua, Y. Guo, Y. Wang, G. C. Chu, P. Li, J. Shi *. Acyl azide modification of the ubiquitin C-terminus enables DUB capture. Chem. Commun. 2023, 59, 1333-1336.
